Paul B Savage Selected Research

ceragenins

5/2022	Bactericidal Activity of Ceragenin in Combination with Ceftazidime, Levofloxacin, Co-Trimoxazole, and Colistin against the Opportunistic Pathogen Stenotrophomonas maltophilia.
10/2021	Peanut-Shaped Gold Nanoparticles with Shells of Ceragenin CSA-131 Display the Ability to Inhibit Ovarian Cancer Growth In Vitro and in a Tumor Xenograft Model.
7/2021	Antibacterial and antibiofilm activities of ceragenins against Achromobacter species isolated from cystic fibrosis patients.
1/2021	New β-Lactam Antibiotics and Ceragenins - A Study to Assess Their Potential in Treatment of Infections Caused by Multidrug-Resistant Strains of Pseudomonas aeruginosa.
1/2020	NDM-1 Carbapenemase-Producing Enterobacteriaceae are Highly Susceptible to Ceragenins CSA-13, CSA-44, and CSA-131.
1/2020	Quantification of Synergistic Effects of Ceragenin CSA-131 Combined with Iron Oxide Magnetic Nanoparticles Against Cancer Cells.
8/2019	Comparative In Vitro Activities of First and Second-Generation Ceragenins Alone and in Combination with Antibiotics Against Multidrug-Resistant Klebsiella pneumoniae Strains.
5/2019	Use of ceragenins as a potential treatment for urinary tract infections.
4/2019	Antifungal susceptibilities, in vitro production of virulence factors and activities of ceragenins against Candida spp. isolated from vulvovaginal candidiasis.
4/2018	Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance.

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Paul B Savage Research Topics

Disease

34	Infections 05/2022 - 03/2005
8	Asthma (Bronchial Asthma) 10/2013 - 02/2006
6	Neoplasms (Cancer) 10/2021 - 09/2013
5	Cystic Fibrosis (Mucoviscidosis) 07/2021 - 09/2007
5	Inflammation (Inflammations) 01/2018 - 02/2006
4	Colonic Neoplasms (Colon Cancer) 01/2020 - 09/2013
2	Sepsis (Septicemia) 01/2021 - 03/2003
2	Human Influenza (Influenza) 01/2019 - 01/2011
2	Persistent Infection 03/2018 - 09/2007
2	Mycoses (Diseases, Fungus) 01/2018 - 01/2016
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 07/2011 - 05/2008
1	Ovarian Neoplasms (Ovarian Cancer) 10/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2021
1	Osteomyelitis 03/2021
1	Hypersensitivity (Allergy) 01/2021
1	Hemolysis 01/2021
1	red meat allergy 01/2020
1	Urinary Tract Infections (Urinary Tract Infection) 05/2019
1	Vulvovaginal Candidiasis 04/2019
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2019
1	Gaucher Disease (Gaucher's Disease) 01/2019
1	Communicable Diseases (Infectious Diseases) 01/2019
1	Mucopolysaccharidosis VI (Syndrome, Maroteaux-Lamy) 01/2019
1	Candidiasis (Moniliasis) 08/2018
1	Carcinogenesis 04/2018
1	Breast Neoplasms (Breast Cancer) 04/2018
1	Femoral Fractures (Femoral Fracture) 01/2018
1	Open Fractures (Compound Fracture) 01/2018
1	Suppuration 01/2018
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2018
1	Bacterial Infections (Bacterial Infection) 01/2018
1	Coinfection 07/2017
1	HIV Infections (HIV Infection) 01/2016
1	Hepatitis B 10/2014
1	Bacteremia 01/2014
1	Cross Infection (Nosocomial Infection) 01/2014
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2013

Drug/Important Bio-Agent (IBA)

15	Anti-Bacterial Agents (Antibiotics)IBA 05/2022 - 09/2007
15	cerageninsIBA 05/2022 - 11/2009
8	AntigensIBA 01/2019 - 03/2005
7	ceragenin CSA-131IBA 10/2021 - 01/2018
7	Peptides (Polypeptides)IBA 01/2020 - 09/2007
7	ceragenin CSA-13IBA 04/2018 - 09/2007
6	GlycolipidsIBA 01/2020 - 03/2005
6	CathelicidinsIBA 05/2019 - 03/2013
5	AllergensIBA 01/2019 - 02/2006
4	CytokinesIBA 04/2021 - 01/2012
4	LipidsIBA 01/2019 - 09/2011
3	Antimicrobial PeptidesIBA 04/2018 - 10/2008
3	Actins (F Actin)IBA 01/2018 - 09/2007
3	LipopolysaccharidesIBA 09/2011 - 09/2007
2	Antineoplastic Agents (Antineoplastics)IBA 10/2021 - 04/2018
2	Polysaccharides (Glycans)IBA 04/2021 - 01/2019
2	ChemokinesIBA 01/2021 - 01/2012
2	Carbapenems (Carbapenem Antibiotics)IBA 08/2020 - 01/2014
2	Pharmaceutical PreparationsIBA 01/2020 - 05/2019
2	CSA-90IBA 01/2020 - 01/2018
2	Galactosylceramides (Galactocerebrosides)IBA 01/2019 - 09/2009
2	VaccinesIBA 01/2019 - 10/2014
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 09/2007
2	Colistin (Coly-Mycin)FDA Link 11/2015 - 01/2011
2	Interleukin-33IBA 10/2013 - 01/2012
2	OzoneIBA 08/2013 - 02/2008
2	SteroidsIBA 11/2012 - 09/2007
2	GlycosphingolipidsIBA 09/2012 - 07/2006
2	Interleukin-17 (Interleukin 17)IBA 01/2012 - 07/2011
2	AutoantibodiesIBA 09/2009 - 05/2008
2	alpha-galactosylceramideIBA 03/2009 - 02/2006
2	Proteins (Proteins, Gene)FDA Link 07/2006 - 02/2006
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021
1	GoldIBA 10/2021
1	HaptensIBA 01/2021
1	Poloxamer (Poloxamer 407)IBA 01/2021
1	LactamsIBA 01/2021
1	ferric oxide (iron oxide)IBA 01/2020
1	SolutionsIBA 05/2019
1	Virulence Factors (Pathogenicity Factors)IBA 04/2019
1	Fluconazole (Zonal)FDA LinkGeneric 04/2019
1	CarbohydratesIBA 01/2019
1	Indicators and Reagents (Reagents)IBA 01/2019
1	Lysergic Acid Diethylamide (LSD)IBA 01/2019
1	MicellesIBA 03/2018
1	Deoxyribonucleases (DNase)FDA Link 01/2018
1	Gentian Violet (Violet, Crystal)FDA Link 01/2018
1	CollagenIBA 01/2018
1	GelsolinIBA 01/2018
1	Aspartic Acid (Aspartate)FDA Link 01/2018
1	PeptidomimeticsIBA 01/2018
1	EndotoxinsIBA 01/2018
1	ABX196IBA 10/2014
1	CD40 Ligand (CD40L)IBA 10/2013
1	1- O- beta- D- glucopyranosyl- (2S,2'R,3R,3'E,4E,8E)- N- (2'- hydroxy- 3'- hexadecenoyl)- 9- methyl- 4,8- icosadien- 1,3- diolIBA 10/2013

Therapy/Procedure

4	Therapeutics 01/2022 - 02/2008
2	Immunotherapy 01/2021 - 01/2019
2	Aftercare (After-Treatment) 01/2019 - 12/2011
1	Ligation 01/2021
1	Punctures 01/2021
1	Cell Transplantation 01/2018
1	Bone Wires 01/2018
1	Precision Medicine 01/2015